1. He started a collaboration with director Steven Soderbergh that resulted in the films Out of Sight .
2. In 2004, Cheadle earned critical acclaim for his lead role as Rwandan hotel manager Paul Rusesabagina in the genocide drama film Hotel Rwanda, which was set during the Rwandan Genocide which earned him a nomination for an Academy Award for Best Actor.
3. He stars as Marty Kaan on the Showtime sitcom House of Lies, for which he most recently won a Golden Globe Award in 2013.
4. Cheadle has campaigned to end the genocide in Darfur, Sudan, and co-authored, with John Prendergast, a book about this issue, Not On Our Watch: The Mission to End Genocide in Darfur and Beyond.
5. With George Clooney, Brad Pitt, Matt Damon, David Pressman, and Jerry Weintraub, Cheadle co-founded the Not On Our Watch Project, an organization focusing global attention and resources to stop and prevent mass atrocities.
6. Cheadle was born in Kansas City, Missouri, the son of Bettye , a teacher, and Donald Frank Cheadle, Sr., a clinical psychologist. He has a sister, Cindy, and a brother, Colin.
7. Cheadle graduated in 1982 from East High School in Denver, Colorado where he played saxophone in the jazz band, sang in the choirs and was active in the theatre department, performing in musicals, plays, and several mime shows all under the direction of Catherine Davis.
8. After he graduated from East, Don went on to California Institute of the Arts, graduating with a BFA in Acting.
9. Cheadle first became eligible for his Screen Actors Guild card when he appeared as a burger joint employee in the 1985 comedy Moving Violations. He then appeared in Hamburger Hill in 1987, and played the role of Jack in the April 1, 1988 “Jung and the Restless” episode of Night Court.
10. Although his character was supposed to be 16 years old, Cheadle was 23 at the time.
11. Cheadle then played the role of Rocket in the 1988 movie Colors.
12. Cheadle subsequently played district attorney John Littleton on two seasons of Picket Fences.
13. Cheadle first received widespread notice for his portrayal of Mouse Alexander in the film Devil in a Blue Dress, for which he won Best Supporting Actor awards from the Los Angeles Film Critics Association and the National Society of Film Critics and was nominated for similar awards from the Screen Actors Guild and the NAACP Image Awards.
14. He also starred in the 1997 film Volcano, directed by Mick Jackson.